Today
Run Line
Total
Moneyline
4th
CLE Guardians
Tanner Bibee
0
-1.5
+185
O 5.5
+100
+105
4th
DET Tigers
Jack Flaherty
0
+1.5
−245
U 5.5
−130
−135
4th
MIL Brewers
Aaron Civale
4
-3.5
−110
O 10.5
−130
−720
4th
PIT Pirates
Mike Burrows
1
+3.5
−120
U 10.5
+100
+450
3rd
ATL Braves
AJ Smith-Shawver
2
+2.5
+100
O 12.5
−130
+360
3rd
WAS Nationals
Trevor Williams
5
-2.5
−130
U 12.5
+100
−540
Tomorrow
Run Line
Total
Moneyline
12:10AM
SEA Mariners
George Kirby
-1.5
+120
O 8.5
−105
−135
12:10AM
HOU Astros
Lance McCullers Jr.
+1.5
−142
U 8.5
−115
+114
10:40PM
CHI Cubs
Matthew Boyd
O 8.5
−110
−112
10:40PM
CIN Reds
Hunter Greene
U 8.5
−110
−108
10:40PM
MIL Brewers
Freddy Peralta
O 7
−105
+102
10:40PM
PIT Pirates
Paul Skenes
U 7
−115
−122
11:10PM
CLE Guardians
Slade Cecconi
+114
11:10PM
DET Tigers
Jackson Jobe
−135
11:10PM
LA Dodgers
Clayton Kershaw
O 9
+102
−118
11:10PM
NY Mets
Griffin Canning
U 9
−122
−102
11:40PM
TEX Rangers
Tyler Mahle
O 8
−115
−185
11:40PM
CHI White Sox
Sean Burke
U 8
−105
+154
SAT MAY 24TH
Total
Moneyline
12:10AM
KC Royals
Noah Cameron
O 7.5
−108
+136
12:10AM
MIN Twins
Pablo Lopez
U 7.5
−112
−162
12:10AM
SEA Mariners
Emerson Hancock
O 8.5
−115
+102
12:10AM
HOU Astros
Ryan Gusto
U 8.5
−105
−122
12:15AM
ARI Diamondbacks
Zac Gallen
O 8.5
−108
−125
12:15AM
STL Cardinals
Miles Mikolas
U 8.5
−112
+105
1:38AM
MIA Marlins
Sandy Alcantara
O 8.5
−102
+124
1:38AM
LA Angels
Yusei Kikuchi
U 8.5
−118
−148

MLB Betting News

Best George Kirby prop bet for Astros vs. Mariners on Thursday 5/22/25
10:30 PM · May 22, 2025
I've got my preview, prediction, and best bet for this Thursday night baseball game between the Astros and the Mariners already published here at DKN, which you can check out at the link. The biggest storyline at Daikin Park tonight might be the return of Mariners' young 1B (to Logan Gilbert's 1A) ace, George Kirby,... The post Best George Kirby prop bet for Astros vs.
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Author(s): Dan Johnson.
Best Julio Rodriguez prop bet for Astros vs. Mariners on Thursday 5/22/25
10:30 PM · May 22, 2025
I've got my preview, prediction, and best bet for this Thursday night baseball game between the Astros and the Mariners already published here at DKN, which you can check out at the link. Having said that, we're really only interested in the momentum along the arc Julio Rodriguez's season has taken. A predictable lull in... The post Best Julio Rodriguez prop bet for Astros vs.
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Author(s): Dan Johnson.
MLB Prop Bets: Best Player Props & Team Picks for May 22, 2025
8:25 PM · May 22, 2025
Thursday's edition of the MLB Prop Bets article will cover the games beginning at 6:40 p.m. ET. Here, you'll see some of my favorite MLB player props and team picks that you can find on DraftKings Sportsbook. If you want to tail any of these bets, you can click on the headline to be directed...
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Author(s): Steve Buchanan.
Milwaukee Brewers at Pittsburgh Pirates prediction, pick for Thursday 5/22/25
7:54 PM · May 22, 2025
We've got an NL Central battle on Thursday night in Pittsburgh, as the Brewers travel to visit their division rival to begin a four-game series. It would be an understatement to say that these two clubs have struggled to score in recent weeks. In fact, across the past 30 days, Milwaukee ranks 29th in baseball...
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Author(s): Garion Thorne.
Detroit Tigers vs. Cleveland Guardians prediction, pick for Thursday 5/22/25
6:25 PM · May 22, 2025
The Tigers and Guardians are set for an electrifying battle at Comerica Park, where Detroit seeks to build on their commanding lead in the AL Central as these two rivals meet for the first time. Detroit has established itself as the class of the division, sitting at a stellar 33-17 record. Meanwhile, Cleveland is in... The post Detroit Tigers vs.
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Author(s): Dan Johnson.
Houston Astros vs. Seattle Mariners prediction, pick for Thursday 5/22/25
6:06 PM · May 22, 2025
The Mariners enter Houston on Thursday night, looking to extend their strong AL West lead against a struggling Astros team. Seattle has surged to a 28-20 record, powered by their stellar pitching and timely offense. The Astros, sitting at 25-24, are dealing with injuries and inconsistent play, especially with Lance McCullers Jr. on the mound.... The post Houston Astros vs.
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Author(s): Dan Johnson.

MLB Odds and Betting

MLB History

No other American sport has the rich history of the country’s national pastime: baseball dates all the way back to the mid-19th century, and has lived through a Civil War, two World Wars, and a new millennium. There’s a reason it has been able to withstand the test of time—relatively easy to understand, baseball is fun to play, fun to watch, has a unique pace, and involves a great deal of strategy. With over a century of rich history and rivalries, there’s no better sport to bet on than Major League Baseball. So grab some peanuts and Cracker Jacks, and let’s talk more about MLB betting.

Biggest Rivalries and Betting Events

World Series

There are no games bigger in baseball than the World Series. The annual, best-of-seven series crowns the greatest team in the Major League, and games are tense, action-packed, and filled with emotion. Make the biggest event in the sport even more exciting with a wager.

MLB Playoffs

To get to the World Series, MLB teams need to get through multiple rounds of playoffs. With rivalries and elimination on the line, these multi-game series are some of the best games baseball has to offer.

New York Yankees vs. Boston Red Sox

The rivalry between the Yankees and Red Sox is one of the most famous in all of sports. As two of the largest markets and most popular teams nationwide, both of these teams attract huge stars and are often American League and World Series contenders. The legend of this rivalry was strengthened after the Red Sox traded Babe Ruth to the Yankees, known as the “Curse of the Bambino,” after which Boston didn’t win another World Series for 86 years.

Los Angeles Dodgers vs. San Francisco Giants

Known as the “Battle of the Bay,” the rivalry between the Giants and the Dodgers dates back to the late 19th century, when both teams were located in New York City and were known as the New York Giants and Brooklyn Dodgers. Since moving to the west coast in the 1950s, the rivalry has been fueled by success and proximity. The series has been marked by a number of notable events, perhaps the most famous being the “Shot Heard Round the World,” when Bobby Thomson hit a walk-off home run for the Giants in 1951 to win the National League pennant.

Types of MLB Bets

With several ways to bet on baseball and add excitement to the game, it’s no wonder MLB betting is so popular among sports fans. You can bet on everything from the outcome of the game and overall season results to the performance of a single player. Learn more about the types of baseball bets that suit you, and have fun.

Spreads or run lines

If you think your favorite team is going to win big on a given day, bet on them to beat the spread! A point spread, also known as a runline in baseball, is the amount by which a team is favored to win. Runlines are commonly set at 1.5. However, some sites, such as DraftKings, allow alternative lines that are based on the matchup.

If a team is listed as +1.5, it means they are the underdog. For example, if the Toronto Blue Jays are playing the New York Mets, and the Blue Jays are listed at -1.5, they need to win by two or more runs to cover the spread. If the Mets are listed at +1.5, they need to either lose by just one run or win the game to cover the spread.

Moneylines

For most American sports, spreads are the most popular bets. The moneyline is a straight up bet on which team will win the game outright. The score doesn’t matter, only who comes out ahead. A bet's payout depends on the odds. Heavier favorites are more likely to win but don't pay as much; underdogs are a more risky bet but pay more.

Three-way moneylines

A three-way moneyline gives three possible outcomes: Team A wins, Team B wins, or the two teams tie. Three-way moneylines are bets on nine innings, since a baseball game can’t end in a tie. If the two teams are tied after nine innings, it’s considered a tie for the three-way moneyline bet, and the winner in extra innings doesn’t matter.

Over/under

Also known as Totals, over/unders are one of the more common bets in baseball.. For example, if the over/under of the Mets vs. Blue Jays game is set at 8.5, that means the teams would have to score a combined nine runs or more to be considered over. Eight or less and the under bettors are winners.

Player props

If you enjoy following individual players, player props are for you. Prop bets are wagers on a specific aspect of a game. A player prop focuses on a single player’s performance, like if he hits a home run in any given game.

Parlay Bets

In a parlay, two or more bets are combined into a single wager. Parlays pay higher than if each bet was placed separately, but they also come with more risk since all bets have to win for the parlay to be a winner. The more bets in a parlay, the greater the difficulty, but bigger the payout.

Parlays can include all kinds of bets, such as runlines, moneylines, or over/unders. Check out our How to Bet 101 guide for an example of a parlay bet.

Futures

Futures are wagers on the entire season, or remainder of the season if it's in progress. The most popular baseball futures bet is who will win the World Series. Futures typically pay well because it’s tough to select a winner months in advance. A lot can change in a season, from trades to injuries. The beauty of futures is they add excitement to the overall season instead of a single game, so you can remain invested all season long.

MLB Teams