MEN'S COLLEGE BASKETBALL TEAMS

SOCCER TEAMS

NFL ODDS WEEK 2

No bets available. Go back home.

NFL ODDS WEEK 2 Betting News

NFL Week 2 MNF Best Bets: Titans vs. Bills, Vikings vs. Eagles Picks, Predictions, Odds on DraftKings Sportsbook
4:29 PM · Sep 19, 2022
NFL Week 2 MNF Best Bets: Titans vs. Bills, Vikings vs. Eagles Picks, Predictions, Odds on DraftKings Sportsbook
After featuring one MNF contest in Week 1, the NFL has two slated for Week 2. (Because why not?) Here are my DraftKings Sportsbook picks for Titans-Bills and Vikings-Eagles.
Author(s): Nick Friar. Photo by David Berding/Getty Images
NFL Week 2 DraftKings Sportsbook Pool Predictions
7:01 PM · Sep 16, 2022
NFL Week 2 DraftKings Sportsbook Pool Predictions
If you’re looking to combine sports betting and DFS, DraftKings Sportsbook Pools are for you. It combines your knowledge of sports betting with the upside of a DFS-style prize pool.
Author(s): Matt LaMarca. Photo by Daniel Bartel-USA TODAY Sports
2022 Week 2 NFL Spread Picks, Predictions, Game Previews, Survivor Picks
10:04 PM · Sep 15, 2022
2022 Week 2 NFL Spread Picks, Predictions, Game Previews, Survivor Picks
Pat Mayo, Geoff Fienberg and Tim Anderson go game-by-game and make their 2022 NFL Week 2 picks against the spread while providing their Week 2 NFL game previews. Plus, a mini Cust Corner on elevators.
Author(s): Pat Mayo. Photo by Eric Espada/Getty Images

NFL Week 2 Odds and Betting

Week 2 of the 2022 NFL season begins on Thursday September 15 with a premiere AFC and AFC West matchup between the Kansas City Chiefs and Los Angeles Chargers. The Chiefs and Chargers both enter Week 2 on a high note after recording road victories in Week 1 against playoff-contending teams, and they’ll square off on Thursday in a game with significant playoff implications. Patrick Mahomes and Justin Herbert are both off to strong starts this season and remain two of the favorites for the 2022 NFL MVP.


There weren’t many large spreads in Week 1 but Week 2 has a few and there are some teams bordering on double-digit favorites. Despite a Packers loss and a Bears win in Week 1, the Packers are favored by around ten points for their NFC North matchup on Sunday Night Football. The other big favorites are the Bills over the Titans, the Rams over the Falcons, the Bengals over the Cowboys and the Broncos over the Texans. The Bengals being large favorites in Dallas is especially notable with the Cowboys actually opening as favorites for the game, but the injury to Dak Prescott in Week 1 has dramatically shifted the line for the game.