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NFL Week 10 Odds and Betting

Week 10 of the 2023 NFL season kicks off with a Thursday Night Football matchup between the Carolina Panthers and Chicago Bears. It’s a battle between two of the worst teams in the league from a record standpoint, but each squad features a young quarterback suiting up with something to prove. The Bears are slim favorites at home.

The San Francisco 49ers are looking to reset coming off their bye after dropping three straight games, but it won’t be an easy task against the red-hot Jacksonville Jaguars. Trevor Lawrence and company have won five straight contests, yet they check in as home underdogs in this highly-anticipated matchup.

The 4 p.m. (ET) slate is headlined by a game between two of the league’s most electrifying offenses in the Detroit Lions and Los Angeles Chargers. After a slow start to the season, Justin Herbert and crew have battled back to .500, while the Lions boast one of the best records in football at 6-2. Dan Campbell’s team is a slight road favorite in Los Angeles.

Week 10 concludes with a Monday Night Football game between the Denver Broncos and Buffalo Bills. It’s been tough sledding for the Bills so far this year, as they sit just one game above .500 after losing to the Bengals. That said, they still enter this week’s matchup as sizable favorites despite the Broncos’ current two-game win streak.