NFL ODDS WEEK 12

  • The Seattle Seahawks are 4.5 point favorites at the New England Patriots on February 8, 2026. The Over-Under Total is 45.5 Points
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NFL Week 12 Odds & Betting

Find NFL odds for Week 12 on DraftKings Sportsbook!

 

NFL Week 12 begins on Thursday Night Football with a matchup of two AFC Wildcard contenders as the Buffalo Bills take on the Houston Texans. Josh Allen, a perennial favorite in the NFL MVP odds, will look to keep up his stellar season while the Texans continue to try to sneak out close wins with backup quarterback Davis Mills.

 

Highlighting the Sunday slate is a showdown between the new face of the AFC, the Indianapolis Colts, and the longtime kinds of the AFC, the Kansas City Chiefs. Expect a lot of fireworks between Patrick MahomesRashee RiceTravis KelceDaniel Jones, and Jonathan Taylor, as this game features the highest Over/Under total of the week.

Monday Night Football will feature two of the hottest teams in the NFC as the San Francisco 49ers host the Carolina Panthers. Bryce Young and Rico Dowdle look to carry the blossoming Panthers against a Brock Purdy and Christian McCaffrey duo that has dominated the conference the last few years.

 

Find these games and more Week 12 NFL odds on DraftKings Sportsbook!