Find NFL odds for Week 4 on DraftKings Sportsbook!

Week 4 kicks off with an AFC North rivalry as Aaron Rodgers and the Pittsburgh Steelers travel to Cleveland to face the Browns on Thursday Night Football. Division rivals always bring extra intensity, and the latest NFL Week 4 odds project a competitive matchup between the Steelers and Browns.

Highlighting Sunday's slate is the NFL's first international game in London this season, where the Indianapolis Colts and Washington Commanders square off at Tottenham Hotspur Stadium. The annual London series returns with two teams looking to build momentum early in the season in front of an international audience. The latest NFL week 4 odds project yet another close matchup. 

Week 4's primetime action continues with Jared Goff and the Detroit Lions traveling to Carolina to take on Bryce Young and the Panthers on Sunday Night Football before Monday Night Football closes out the week with an NFC South rivalry between the Atlanta Falcons and New Orleans Saints.