NFL ODDS WEEK 16

Find NFL odds for Week 16 on DraftKings Sportsbook!

Week 16 of the NFL season kicks off on Thursday Night Football with a much anticipated NFC West matchup as the Los Angeles Rams visit the Seattle Seahawks. The squads are neck and neck for the top spot in both the division and the conference, and that’s evident by the odds in this matchup, as this is projected to be the closest game of the week with almost dead even moneyline odds.

The NFL on Saturday is back! On Saturday night we’ll see one of the league’s most storied rivalries between the Green Bay Packers and Chicago Bears. This is the second closest matchup of the week based on the moneyline odds, as Jordan Love and Caleb Williams compete for control of the NFC North.

Another division leader is up for grabs on Sunday when the Tampa Bay Buccaneers visit the Carolina Panthers. Baker Mayfield and the Bucs have had the NFC South in their pocket for the last couple of years, but Bryce Young and the up and coming Panthers look to change that.

Week 16 will conclude on Monday Night Football when the San Francisco 49ers visit the Indianapolis Colts. The biggest story in December right now is the return of 44-year-old Philip Rivers, 5 years after his retirement. Can he be the lifeline for the Colts or will the favored 49ers led by Brock Purdy take care of business?

Find these games and more Week 16 NFL odds on DraftKings Sportsbook!