No bets available. Go back home.

NFL Week 1 Odds and Betting

The 2022 NFL preseason is underway as football players across the league go through their final tune-ups before the regular season begins in September. Week 1 odds have been available for several weeks now, and the season will begin with an intriguing matchup between two Super Bowl contenders in the Buffalo Bills and Los Angeles Rams on Thursday September 8. The Bills have held as small favorites since this line opened, an extremely rare occurrence for a team that’s facing the defending Super Bowl champions on their home turf. The Bills begin the 2022 season at the top of the board for Super Bowl odds, with the Rams just fifth despite winning it all in 2021. Rounding out the rest of the top five are the Tampa Bay Buccaneers, Kansas City Chiefs and Green Bay Packers.

Betting markets for leaders in various statistical categories have been released as well, and Justin Herbert of the Los Angeles Chargers is the favorite to lead the league in passing yards for the 2022 season. Herbert is at the top in terms of odds for passing touchdowns as well, while Jonathan Taylor of the Indianapolis Colts has the shortest odds for both rushing yards and rushing touchdowns. For receiving leaders, Justin Jefferson is the favorite to have the most yards but Ja’Marr Chase is the favorite to haul in the most touchdowns, while Cooper Kupp is actually the favorite to lead the NFL in receptions.